Cystic Fibrosis: Improving quality of life

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Author Details : Sunil Chaudhry*

Volume : 8, Issue : 2, Year : 2021

Article Page : 91-96

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Cystic Fibrosis (CF) or Mucoviscidosis is an inherited condition. In cystic fibrosis transmembrane conductance regulator (CFTR) protein does not functions properly i.e regulation of fluids and salts outside the cells. Cystic fibrosis affects exocrine glands eg., the mucus-secreting and sweat glands in the respiratory and digestive systems. The frequency of common mutation F508del (deletion of phenylalanine residue at position 508) in children is between 19% and 34%. The estimate frequency of CF as 1:10,000 to 1:40,000 in children. There is no cure for cystic fibrosis, but treatment can reduce symptoms and complications to improve quality of life. Close monitoring and early, aggressive intervention is recommended to slow the progression of CF, which can lead to possible longer life.

Keywords: Cystic fibrosis transmembrane conductance regulator (CFTR) protein, Pseudomonas aeruginosa, Sweat Chloride, Pancreatic enzyme replacement therapy, Ivacaftor.

How to cite : Chaudhry S, Cystic Fibrosis: Improving quality of life. J Community Health Manag 2021;8(2):91-96

Copyright © 2021 by author(s) and J Community Health Manag. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (

Article History

Received : 26-04-2021

Accepted : 11-06-2021

Available online : 27-07-2021

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